WormBase Tree Display for Expr_pattern: Expr11973
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| Expr11973 | Expression_of | Gene | WBGene00006755 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006755 | |||
| Expression_data | Anatomy_term | WBbt:0005190 | Certain | |
| WBbt:0006840 | Certain | |||
| Type | Reporter_gene | Two-color splicing reporter. | ||
| Pattern | A striking differential splicing pattern was observed with a reporter monitoring alternative exon 16 of unc-16/JIP3 in the ventral nerve cord, which is composed of excitatory cholinergic and inhibitory GABAergic motor neurons. The exon-16-included isoform is expressed in both cholinergic and GABAergic neurons, while the excluded isoform is expressed only in GABAergic neurons, confirmed by coexpressing a codon-optimized enhanced blue fluorescent protein (eBFP) in GABAergic neurons. | |||
| Picture | WBPicture0000013711 | |||
| Reference | WBPaper00045350 |
