WormBase Tree Display for Expr_pattern: Expr12083
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| Expr12083 | Expression_of | Gene | WBGene00006887 | ||
|---|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006887 | ||||
| Expression_data | Anatomy_term | WBbt:0003955 | Certain | ||
| WBbt:0005021 | Certain | ||||
| WBbt:0005027 | Certain | ||||
| WBbt:0006840 | Partial | ||||
| Remark | Variable reporter expression was observed in cholinergic motor neurons in the ventral nerve cord | ||||
| Not_in_Anatomy_term | WBbt:0003826 | ||||
| WBbt:0003827 | |||||
| WBbt:0003903 | |||||
| WBbt:0003904 | |||||
| WBbt:0006746 | |||||
| WBbt:0007804 | |||||
| Type | Reporter_gene | ||||
| Pattern | In five independent reporter lines generated, fluorescence was regularly observed in the ALA interneuron. In addition, variable reporter expression was observed in cholinergic motor neurons in the ventral nerve cord but not in GABA motor neurons of the ventral nerve cord. Rather, the vav-1 reporter was expressed in two GABA motor neurons in the head, known as RME dorsal and RME ventral, which regulate head oscillations. Several cell types were found to be negative for vav-1 reporter expression. The tested vav-1 reporters did not show co-expression with markers of dopaminergic neurons (Pdat-1::GFP), command interneurons of the locomotory circuit, which directly activate motor neurons (Pglr-1::RFP) or with a marker of a small set of sensory neurons (AWC and ASE neurons, marked by Pceh-36::RFP). In sum, fluorescent vav-1 reporters are expressed in a small subset of neurons that comprise multiple cell types, including an interneuron, cholinergic motor neurons and a small subset of GABAergic motor neurons. | ||||
| Reference | WBPaper00046036 | ||||
| Transgene | WBTransgene00020566 |
