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WormBase Tree Display for Expr_pattern: Expr1253

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Name Class

Expr1253Expression_ofGeneWBGene00006595
Reflects_endogenous_expression_ofWBGene00006595
Expression_dataLife_stageWBls:0000003
WBls:0000057
Anatomy_termWBbt:0005772Certain
WBbt:0006797Certain
GO_termGO:0031616
Subcellular_localizationIn the dividing cells of early embryos, the protein was distinctively localized in centrosomes (1 cell to 4 cell embryos). The protein localization in centrosomes was observed throughout mitosis from prophase to telophase.
TypeAntibodyRabbit antiserum against the 25KDa C-terminal polypeptide fragment.
PatternIn the meiotic cells of the gonad including oocytes and in the interphase cells of 200-cell embryos, DNA topoisomerase I was localized in nuclei. At the comma stage, a more narrowed concentration of DNA topoisomerase I was observed in the nucleoli of gut cells.
ReferenceWBPaper00004689
Antibody_infoWBAntibody00000181