Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Expr_pattern: Expr12884

expand all nodes | collapse all nodes | view schema

Name Class

Expr12884Expression_ofGeneWBGene00003939
Reflects_endogenous_expression_ofWBGene00003939
Expression_dataLife_stageWBls:0000024Anatomy_termWBbt:0006770
WBbt:0006771
WBbt:0006774
WBbt:0006775
WBbt:0006776
WBbt:0006777
WBbt:0006778
WBbt:0006779
WBls:0000003Anatomy_term (13)
WBls:0000038Anatomy_termWBbt:0006768
Anatomy_term (24)
TypeReporter_gene
Patternpax-3 reporter expression was first observed around 240 min post first cleavage in AB-derived cells. Specifically, on the left side of the embryo expression was seen in hyp4, hyp6, two hyp 7 cells, P1/2 L, P3/4 L, seam cell V3L, P5/6 L, P7/8 L, P9/10 L, and four cells clustered at the posterior end of the embryo (TL, hyp 7, PVQL, PHBL). pax-3 reporter expression continued in many of these cells to the end of embryogenesis. In agreement with Liu et al., in the newly hatched L1 larva pax-3 reporter expression was seen in eight of twelve P cells (P1/2, P5/6, P7/8, P9/10) (Liu et al., 2009). Interestingly pax-3 reporter expression in P cell pairs P3/4 begins to fade in the embryo and is absent in the L1 stage, and expression was never observed in P cell pair P11/12. pax-3 reporter expression continued in the Pn.a and Pn.p descendants of these P cells in the L2 stage, but disappeared in the P cell descendants by the beginning of the L3 stage. Using the rescuing pax-3p::pax-3::gfp reporter, evidence of pax-3 expression was also observed in the VulF cells of the L4 stage developing vulva, in the migrating sex myoblasts (SM) and their descendants, and in the developing male tail. In summary, pax-3 expression was seen throughout embryogenesis and early larval development predominantly in hypodermal cells, in particular the ventral P hypodermal cells.
ReferenceWBPaper00049356
TransgeneWBTransgene00015729