WormBase Tree Display for Expr_pattern: Expr13186

Expr13186 Expression_of: Gene: WBGene00013039
    Reflects_endogenous_expression_of: WBGene00013039
  Expression_data: Life_stage: WBls:0000002 Anatomy_term: WBbt:0003681
          WBbt:0005733
          WBbt:0005741
          WBbt:0005828
          WBbt:0006748
    Anatomy_term: WBbt:0003681 Certain
        Life_stage: WBls:0000002
      WBbt:0005733 Certain
        Life_stage: WBls:0000002
      WBbt:0005741 Certain
        Life_stage: WBls:0000002
      WBbt:0005828 Certain
        Life_stage: WBls:0000002
      WBbt:0006748 Certain
        Life_stage: WBls:0000002
    GO_term: GO:0005764
  Subcellular_localization: SCAV-3::GFP labeled both puncta and tubular structures that were positive for NUC-1 and LAAT-1, suggesting that SCAV-3 localizes to lysosomes. SCAV-3(AAA)::GFP, in which the C-terminal leucine-based lysosomal targeting motif (Leu516-Val517-Leu518) was replaced by three alanines, mostly stained plasma membranes, further suggesting that SCAV-3 is a lysosomal membrane protein.
  Type: Reporter_gene
  Pattern: SCAV-3::GFP is widely expressed during embryonic, larval, and adult stages in various tissues including pharynx, hypodermis, gonadal sheath cells, vulva, and tail region. SCAV-3::GFP was not evident in the intestine and was only very weakly expressed in body wall muscle cells.
  Picture: WBPicture0000014448
  Reference: WBPaper00050406
  Transgene: WBTransgene00023656