WormBase Tree Display for Expr_pattern: Expr13241
expand all nodes | collapse all nodes | view schema
| Expr13241 | Expression_of | Gene | WBGene00006780 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006780 | ||
| Expression_data (3) | |||
| Type | Genome_editing | ||
| Reporter_gene | |||
| Pattern | In contrast to UNC-44C::GFP, we did not detect expression of UNC-44L::GFP(ju1412) before the bean stage of embryogenesis. By the 1.5-fold stage of embryogenesis, we observed expression of UNC-44L::GFP mainly in the developing nervous system. UNC-44L::GFP became progressively more concentrated in the nervous system, predominantly localizing to neuronal processes and to the peripheries of neuronal cell bodies. UNC-44L has been previously thought to be exclusively neuronal, based on immunostaining experiments. However, we observed faint expression of UNC-44L::GFP in epidermal seam cells at the L4 stage, and in the gonadal anchor cell at L3 stage, as well as in neighboring vulval cells at L4. Thus the regulation of UNC-44L is temporally and spatially distinct from the more widely expressed UNC-44 isoforms, and is predominantly but not exclusively confined to neurons. | ||
| Reference | WBPaper00050654 | ||
| Variation | WBVar02147612 |
