WormBase Tree Display for Expr_pattern: Expr15548
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| Expr15548 | Expression_of | Gene | WBGene00020466 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00020466 | |||
| Expression_data | Anatomy_term | WBbt:0004015 | Certain | |
| WBbt:0005906 | Certain | |||
| WBbt:0005994 | Certain | |||
| WBbt:0006873 | Certain | |||
| WBbt:0006874 | Certain | |||
| WBbt:0006876 | Certain | |||
| GO_term | GO:0005634 | |||
| Type | Reporter_gene | |||
| Pattern | Both SLD-3 and SLD-2 showed asymmetric localisation, with more protein in the AB cell nucleus, than P1. This asymmetry was not limited to the MosSCI alleles, as we obtained a similar result using immuno-fluorescence of endogenous SLD-2. Asymmetric and asynchronous divisions continue beyond the two-cell stage, with the descendants of the AB cell (ABa and ABp) having shorter cell cycles than the descendants of the P1 cell (EMS and P2) with P2 having the longest S-phase of these cells. We analysed the abundance of SLD-2 and SLD-3 in 4-cell stage embryos and these two proteins remained asymmetric at this stage with EMS and P2 having significantly less protein than the AB cell lineage. SLD-2 abundance was also significantly lower in the P2 cell than the EMS cell. | |||
| Reference | WBPaper00060777 | |||
| Transgene | WBTransgene00019624 |
