WormBase Tree Display for Expr_pattern: Expr15691

Expr15691 Expression_of: Gene: WBGene00002992
    Reflects_endogenous_expression_of: WBGene00002992
  Expression_data: Life_stage: WBls:0000027 Anatomy_term: WBbt:0004522
      WBls:0000035 Anatomy_term: WBbt:0004522
    Anatomy_term: WBbt:0004522 Certain
        Life_stage: WBls:0000027
          WBls:0000035
    GO_term: GO:0045180
  Type: Reporter_gene
  Pattern: In L2 and L3 larvae, mNGr::LIN-3 expression was detected in intracellular punctae and on the basal cortex of the AC. No extracellular mNGr::LIN-3 signal could be detected, suggesting that the majority of mNGr::LIN-3 remains attached to the AC surface after its secretion to the plasma membrane, or that a cleavage product of the mNGr::LIN-3 protein is released from the AC and rapidly taken up by the adjacent VPCs or degraded. The same localization pattern was observed with a multicopy GFP::LIN-3 transgene (zhIs67), in which the GFP tag had been inserted at the same position as in the endogenous mNGr::lin-3(zh112) reporter strain. In wild-type larvae, mNGr::LIN-3 was enriched towards the ventral cortex of the AC from the mid-L2 stage until the mid-L3 stage.
  Reference: WBPaper00059670
  Transgene: WBTransgene00026882