WormBase Tree Display for Expr_pattern: Expr15836
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Expr15836 | Expression_of | Gene | WBGene00003915 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00003915 | |||
Expression_data | Life_stage | WBls:0000003 | ||
WBls:0000041 | ||||
WBls:0000023 | ||||
Anatomy_term | WBbt:0005753 | Certain | ||
GO_term | GO:0005886 | |||
GO:0005737 | ||||
Type | Genome_editing | |||
Reporter_gene | ||||
Pattern | PAN-1GFP signal was detected broadly in embryos and early larvae, but decreased substantially in late larvae and adults. Two types of PAN-1GFP subcellular patterns were observed: at the cell membrane and as cytoplasmic puncta. Some prominent PAN-1GFP signal was found in seam cells, a type of epidermal cells that shows stem-cell like division during larval development. These cells were lined up in a single profile at each lateral line and embedded in syncytial epidermis. Between the seam cells and the epidermis, a ring of tight junctions formed on the apical-lateral side of the cells. By colabelling a tight-junction component DLG-1::RFP and PAN-1GFP, we observed that PAN-1 distributed at the lateral basal membrane of seam cells. PAN-1 is also localized on the cell membrane of many ventral cord neurons, including DD neurons at L1 and L2. Therefore, we observed that PAN-1 is localized on the cell membrane. | |||
Reference | WBPaper00061377 | |||
Variation | WBVar02157206 |