WormBase Tree Display for Expr_pattern: Expr15837

Expr15837 Expression_of: Gene: WBGene00003915
    Reflects_endogenous_expression_of: WBGene00003915
  Expression_data: Life_stage: WBls:0000024 Anatomy_term: WBbt:0005270
          WBbt:0005300
      WBls:0000027 Anatomy_term: WBbt:0005270
          WBbt:0005300
    Anatomy_term: WBbt:0005270 Certain
        Life_stage: WBls:0000024
          WBls:0000027
      WBbt:0005300 Certain
        Life_stage: WBls:0000024
          WBls:0000027
  Type: Genome_editing
    Reporter_gene
  Pattern: PAN-1GFP signal was detected broadly in embryos and early larvae, but decreased substantially in late larvae and adults. Two types of PAN-1GFP subcellular patterns were observed: at the cell membrane and as cytoplasmic puncta. Some prominent PAN-1GFP signal was found in seam cells, a type of epidermal cells that shows stem-cell like division during larval development. These cells were lined up in a single profile at each lateral line and embedded in syncytial epidermis. Between the seam cells and the epidermis, a ring of tight junctions formed on the apical-lateral side of the cells. By colabelling a tight-junction component DLG-1::RFP and PAN-1GFP, we observed that PAN-1 distributed at the lateral basal membrane of seam cells. PAN-1 is also localized on the cell membrane of many ventral cord neurons, including DD neurons at L1 and L2. Therefore, we observed that PAN-1 is localized on the cell membrane.
  Reference: WBPaper00061377
  Variation: WBVar02157206