WormBase Tree Display for Expr_pattern: Expr15941
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| Expr15941 | Expression_of | Gene | WBGene00002245 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00002245 | |||
| Expression_data | Anatomy_term | WBbt:0006892 | Certain | |
| WBbt:0006893 | Certain | |||
| WBbt:0006894 | Certain | |||
| WBbt:0006895 | Certain | |||
| WBbt:0006896 | Certain | |||
| Type | Genome_editing | |||
| Reporter_gene | ||||
| Pattern | LAG-1::mKate2, revealed a dynamic expression pattern in the VPCs during vulval induction. In order to achieve a more quantitative analysis, and potentially reveal more subtle dynamics, we quantitated LAG-1::GFP fluorescence, as GFP appeared brighter overall than mKate2. We observed that both LAG-1::GFP and LAG-1::mKate2 accumulated to a higher level in P5.p and P7.p compared with other VPCs (secondary fate pattern). This accumulation pattern is consistent with LIN-12 activation in the VPCs and suggests a positive feedback mechanism. | |||
| Reference | WBPaper00060145 | |||
| Variation | WBVar02153349 | |||
| WBVar02156837 |
