WormBase Tree Display for Expr_pattern: Expr1603
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| Expr1603 | Expression_of | Gene | WBGene00004212 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004212 | |||
| Expression_data | Life_stage | WBls:0000022 | ||
| WBls:0000015 | ||||
| WBls:0000021 | ||||
| Anatomy_term | WBbt:0003832 | Certain | ||
| WBbt:0003953 | Certain | |||
| WBbt:0003954 | Certain | |||
| WBbt:0004103 | Certain | |||
| WBbt:0004104 | Certain | |||
| Type | Antibody | Affinity-purified rabbit polyclonal anti-PTL-1 serum 14 was used to examine the distribution of both isoforms of PTL-1 during C. elegans development. | ||
| Pattern | Staining was observed in the epidermis of embryos undergoing elongation, but not after hatching. In addition, weak staining was observed in a number of neurons within the head region. During larval and adult stages, mechanosensory neurons and their processes express PTL-1. The number and position of immunoreactive neurons were examined in six late first or second stage larvae, when six mechanosensory cells are present. In six out of six animals, five of these neurons stained for PTL-1 (neurons ALML, ALMR, AVM, PLML and PLMR). Thus, with the exception of PVM, all mechanosensory neurons express PTL-1. Mechanosensory neurons stained for the remainder of development, but their number was not counted after the L2 stage. PTL-1 staining was specific, as it was completely abolished following pre-adsorption of the diluted antibody with recombinant PTL-1. | |||
| Picture | WBPicture0000011616 | |||
| Reference | WBPaper00002601 | |||
| Antibody_info | WBAntibody00000130 |
