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WormBase Tree Display for Expr_pattern: Expr1605

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Name Class

Expr1605Expression_ofGeneWBGene00001599
WBGene00001598
Reflects_endogenous_expression_ofWBGene00001598
WBGene00001599
Expression_dataLife_stageWBls:0000002
Anatomy_termWBbt:0005175Certain
WBbt:0005784Certain
TypeIn_situIn situ hybridizations were performed to adult hermaphrodites, males, and embryos.
PatternIn adults, glh-1 and glh-2 RNAs are restricted to germ-line tissue. glh-1 RNA is present at all stages of germ-line development in the hermaphrodite gonad, from the distal region where germ cells divide mitotically through the proximal region where gametes mature. A similar pattern of strong glh-1 hybridization to all regions of the germ line is observed in males.
The glh-2 message is at least 3-fold less abundant than glh-1 mRNA in the hermaphrodite germ line. The glh-2 signal is weakest in the distal mitotic region and most concentrated in the central meiotic region of the gonad. In addition, glh-2 RNA is barely detectable in males. Both glh-1 and glh-2 RNAs are detected in all cells of young embryos, with the level of hybridization much reduced after the 8- to 10-cell stage. Thus, while glh-1 and glh-2 RNA differ in their levels and their patterns of accumulation in hermaphrodite and male germ lines, both glh RNAs are found throughout the early embryo.
PictureWBPicture0000011619
ReferenceWBPaper00002611