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WormBase Tree Display for Expr_pattern: Expr16291

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Name Class

Expr16291Expression_ofGeneWBGene00004219
Reflects_endogenous_expression_ofWBGene00004219
Expression_dataLife_stageWBls:0000038Anatomy_termWBbt:0005734
WBbt:0005753
WBbt:0005773
WBbt:0006748
WBbt:0007832
WBls:0000019Anatomy_termWBbt:0003672
WBbt:0005773
WBbt:0005777
WBbt:0005778
WBls:0000020Anatomy_termWBbt:0003672
WBbt:0005773
WBbt:0005777
WBbt:0005778
WBls:0000021Anatomy_termWBbt:0003672
WBbt:0005773
WBbt:0005777
WBbt:0005778
Anatomy_termWBbt:0003672Certain
Life_stageWBls:0000019
WBls:0000020
WBls:0000021
WBbt:0005734Certain
Life_stageWBls:0000038
WBbt:0005753Certain
Life_stageWBls:0000038
WBbt:0005773Certain
Life_stageWBls:0000019
WBls:0000020
WBls:0000021
WBls:0000038
WBbt:0005777Certain
Life_stageWBls:0000019
WBls:0000020
WBls:0000021
WBbt:0005778Certain
Life_stageWBls:0000019
WBls:0000020
WBls:0000021
WBbt:0006748Partial
Life_stageWBls:0000038
Remarksome cells in the vulva
WBbt:0007832Certain
Life_stageWBls:0000038
GO_termGO:0016324
Subcellular_localizationPTR- 4::SfGFP was not detected during the early part of embryogenesis but appeared by the twofold stage along the apical membranes of the epidermis, excretory duct and pore, and rectum. However, PTR-4 expression was transient and rapidly cleared prior to hatching. PTR-4 reappeared in the middle of each subsequent larval stage, during the time when precuticle is present. During L4 stage, the stage pre- ceding adulthood, PTR-4 was present on apical surfaces between the major epidermis (hyp7) and the lateral seam cells (Figure 5E), which secrete alae (as well as precuticle factors that are needed to shape alae; Lie ́geois et al. 2006; Kolotuev et al. 2009; Forman- Rubinsky et al. 2017; Cohen et al. 2019; Flatt et al. 2019). PTR-4 was also present along apical surfaces of the rectum and of some cells in the vulva, the tube through which eggs will be laid. As in embryogenesis, PTR-4 was transient and disappeared as the adult cuticle was made. Together, these observations demon- strate that PTR-4 is present on the apical surfaces of external epithelia during the time period when precuticle is present.
TypeGenome_editing
Reporter_gene
ReferenceWBPaper00062109
VariationWBVar02157572