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WormBase Tree Display for Expr_pattern: Expr1870

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Name Class

Expr1870Expression_ofGeneWBGene00000476
Reflects_endogenous_expression_ofWBGene00000476
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000019
WBls:0000020
WBls:0000021
Anatomy_term (18)
GO_termGO:0005634
Subcellular_localizationCFI-1 protein is localized to nuclei of staining cells.
TypeAntibodyRat antibodies against the CFI-1 ARID and examined CFI-1 expression by whole-mount immunofluorescence.
PatternExpression of CFI-1 was identified in mid-late embryos (twofold and later) and throughout larval development and in the adult. CFI-1 was expressed in a small number of cells in the head and tail regions of the animals, with occasional faint staining in ventral cord neurons. In the head, only neurons and muscle cells expressed CFI-1. In the tail, only four neuronal cells expressed CFI-1. A cfi-1::GFP fusion gene was expressed in a pattern similar to that observed with anti-CFI-1 antisera. Using the cfi-1::GFP and anti-CFI-1 antisera a number of the cells expressing cfi-1 was identified based on their anatomical positions and neuronal morphologies. CFI-1 protein was expressed in IL2 and URA neurons, and in the AVD and PVC interneurons. Weaker expression was detected in the PVC sister neuron LUA. Most, if not all, head muscle cells expressed CFI-1, and m6 and m7 muscles in the pharynx expressed the protein as well. A small number of other cells also stained occasionally.
PictureWBPicture0000008435
WBPicture0000008437
ReferenceWBPaper00005226
Antibody_infoWBAntibody00000501