WormBase Tree Display for Expr_pattern: Expr2261
expand all nodes | collapse all nodes | view schema
| Expr2261 | Expression_of | Gene | WBGene00003170 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003170 | ||
| Expression_data | Anatomy_term (59) | ||
| GO_term | GO:0005737 | ||
| Subcellular_localization | Cytoplasmic, but not extracellular, b-galactosidase has enzymatic activity. A full-length mec-6::lacZ fusion produced no b-galactosidase activity unless DNA encoding a synthetic transmembrane domain was added. The transmembrane domain-dependent changes in lacZ expression indicate that MEC-6 is a transmembrane protein with its C terminus situated extracellularly. | ||
| Type | Reporter_gene | ||
| Pattern | Many cells, including the six touch receptor neurons, expressed green fluorescent protein (GFP) and b-galactosidase (LacZ) from mec-6 promoter and protein fusions. These fusions were expressed primarily in neurons (the six touch receptors, ventral cord motor neurons, HSN, PVD, PVC, IL1, and several other unidentified neurons near the nerve ring, in the anal ganglion and in the male tail sensory rays), muscles (the body wall, vulval, intestinal, anal depressor and sphincter muscles) and the excretory canal. | ||
| Reference | WBPaper00005591 | ||
| Transgene | WBTransgene00027966 |
