WormBase Tree Display for Expr_pattern: Expr2378
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| Expr2378 | Expression_of | Gene | WBGene00001189 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001189 | ||
| Expression_data | Anatomy_term (15) | ||
| GO_term | GO:0043005 | ||
| GO:0043025 | |||
| Subcellular_localization | In wild-type animals, egl-21 immunostaining was most concentrated in the nerve ring and other neuronal processes, whereas neuronal cell bodies had lower levels of expression. | ||
| Type | Reporter_gene | ||
| Pattern | Immunostaining in wild-type animals showed that EGL-21::GFP is expressed widely in the nervous system, with particularly strong expression in the neuronal processes of the nerve ring. EGL-21::GFP was not expressed in any non-neuronal tissues. | ||
| egl-21 immunostaining was found in ~100 cells in the head and several neurons in the tail ganglia (15+/-3) and pre-anal ganglion (7+/-1) and motor neurons of the ventral cord (38+/-4). The subset of the egl-21 CPE-expressing cells include the following: the mechanosensory neurons ALM, AVM, and PVM; the interneurons BDU, SDQ; and the HSN egg-laying motor neurons. | |||
| Picture | WBPicture0000011104 | ||
| Remark | Immunostaining increased in neuronal cell bodies of unc-104 KIF1A mutants, whereas staining in axons was proportionately diminished. In addition, a broader expression pattern was observed in unc-104 KIF1A mutants compared with wild-type controls, because retention in the cell bodies enabled identification of previously undetected neurons. | ||
| Reference | WBPaper00005776 | ||
| Transgene | WBTransgene00028031 |
