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WormBase Tree Display for Expr_pattern: Expr2706

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Name Class

Expr2706Expression_ofGeneWBGene00001577
Reflects_endogenous_expression_ofWBGene00001577
Expression_dataLife_stageWBls:0000024
WBls:0000003
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
Anatomy_termWBbt:0004574Certain
WBbt:0004575Certain
WBbt:0004576Certain
WBbt:0004577Certain
WBbt:0004697Certain
WBbt:0005319Partial
RemarkStrongly expressed in distal spermatheca cells.
WBbt:0005767Certain
WBbt:0005772Certain
WBbt:0006756Certain
WBbt:0006784Certain
GO_termGO:0005886
GO:0031410
Subcellular_localizationIn cells that express GEM-4::GFP, fluorescence is typically brightest at the plasma membrane. In some cases, punctate staining is also evident within the cytoplasm, possibly due to association with vesicular structures.
TypeReporter_gene
PatternExpression of GEM-4::GFP within Z1 and Z4 becomes progressively more difficult to detect as the animals progress through L1 and is not detectable within the progeny of Z1 and Z4. GEM-4::GFP expresion within somatic gonadal tissues does not resume until early adulthood. At this point, GEM-4::GFP becomes strongly expressed within the distal spermathecal cells, the spermathecal valve cells, and the uterine epithelial cells.
GEM-4::GFP is broadly expressed in embryos that have several hundred cells and continues to be expressed in most cells as the embryo undergoes elongation.
In newly hatched L1s, GEM-4::GFP is expressed in the precursors of the somatic gonad (Z1 and Z4), the pharyngo-intestinal valve cells, the intestinal cells, and the head mesodermal cell (the sister of Z4). The germline precursors, Z2 and Z3, also appear to be outlined in some animals; however, it is not clear whether this is due to expression within the germ cells themselves or whether it results from extensions of the plasma membranes of Z1 and Z4.
PictureWBPicture0000011799
WBPicture0000011800
WBPicture0000011801
WBPicture0000011802
ReferenceWBPaper00006177
TransgeneWBTransgene00028142