WormBase Tree Display for Expr_pattern: Expr2905
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| Expr2905 | Expression_of | Gene | WBGene00004315 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004315 | ||
| Expression_data | Life_stage | WBls:0000024 | |
| WBls:0000003 | |||
| WBls:0000038 | |||
| WBls:0000027 | |||
| WBls:0000035 | |||
| WBls:0000041 | |||
| GO_term | GO:0005730 | ||
| Subcellular_localization | Maternal RBD-1 is seen as a number of granules in the cytoplasm and disappears shortly after cleavage begin. | ||
| To determine the subcellular localization of RBD-1, intestine cells were closely inspected since they have relatively large nuclei, making it possible to easily discriminate the cell compartments. As evidenced by its colocalization with a nucleolar marker protein FIB-1, RBD-1 is localized in the nucleolus. | |||
| Type | Antibody | ||
| Pattern | Immunostaining of embryos shows that RBD-1 expression is limited to late embryonic stages. A small amount of maternally supplied RBD-1 is also detectable in the fertilized egg. In contrast to zygotic RBD-1, maternal RBD-1 is seen as a number of granules in the cytoplasm and disappears shortly after cleavage begin, suggesting that maternal RBD-1 may be degraded rapidly in early embryos. During post-embryonic development, RBD-1 is expressed ubiquitously in L1 larvae and continues to be expressed until adulthood in both somatic and germline cells. | ||
| Remark | FIB-1, a C.elegans homolog of the yeast Nop1p, shows a very similar expression pattern to RBD-1 during C.elegans embryogenesis. | ||
| Reference | WBPaper00006468 | ||
| Antibody_info | WBAntibody00000728 |
