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WormBase Tree Display for Expr_pattern: Expr3478

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Name Class

Expr3478Expression_ofGeneWBGene00020316
Reflects_endogenous_expression_ofWBGene00020316
Expression_dataGO_termGO:0005634
GO:0000794
Subcellular_localizationIn nonirradiated wild-type (N2) animals, CeBRC-2 is diffuse and detected at very low levels in nuclei. However, after radiation treatment, germ line nuclei accumulate a large number of discrete foci concordant with DNA. No signal is detected in Cebrc-2 mutants, demonstrating that the focus formation observed in wild-type animals after radiation treatment is specific to CeBRC-2. These results imply that CeBRC-2 localizes to presumptive sites of DNA damage after radiation treatment.
TypeAntibody
ReferenceWBPaper00025138
Antibody_infoWBAntibody00000837
WBAntibody00000838