WormBase Tree Display for Expr_pattern: Expr3681
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| Expr3681 | Expression_of | Gene | WBGene00011315 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00011315 | ||
| Expression_data | Anatomy_term (20) | ||
| GO_term | GO:0005634 | ||
| Subcellular_localization | The MBR-1::GFP fusion protein was localized to the nuclei, consistent with the idea that MBR-1 functions as a transcription factor. | ||
| Type | Reporter_gene | ||
| Pattern | In strains that carry Pmbr-1::gfp, GFP expression was observed in restricted sets of interneurons in the head ganglia: AIM, RIC, RIH (or RIR), RIF (or RIG), and a pair of interneurons tentatively identified as AIN. Expression was also observed in three interneurons of the tail ganglia: PVP and an interneuron tentatively identified as DVA or DVC. In contrast, mbr-1::gfp was expressed in several more neurons compared to Pmbr-1::gfp, including sensory neurons. Expression of mbr-1::gfp was also detected in some intestinal cells at the late embryonic stages as well as in vulval cells and some somatic gonadal cells at the L4 stage. mbr-1::gfp expression becomes detectable first around the early comma stage, which corresponds to the time just after the birth of most neurons. | ||
| Picture | WBPicture0000009814 | ||
| Remark | The differences in the expression patterns of Pmbr-1::gfp and mbr-1::gfp might be due to the following reasons: first, additional regulatory elements might exist in introns and 3$(B!l(B-UTR regions, which are not included in the former construct; and second, as the product of Pmbr-1::gfp diffuses throughout the cytoplasm, it might be difficult to detect low levels of GFP expression. | ||
| Reference | WBPaper00026753 | ||
| Transgene | WBTransgene00028812 |
