WormBase Tree Display for Expr_pattern: Expr3825
expand all nodes | collapse all nodes | view schema
| Expr3825 | Expression_of | Gene | WBGene00004273 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004273 | ||
| Expression_data | Anatomy_term (11) | ||
| GO_term | GO:0005769 | ||
| Subcellular_localization | The GFP-RAB-10 fusion protein appeared punctate in most tissues. In the intestine GFP-RAB-10 localized to distinct cytoplasmic puncta resembling endosomes that ranged in size from 0.5 to 1.0 um. | ||
| Type | Reporter_gene | [rab-10::gfp] transcriptional fusion and [rab-10::gfp-rab-10] translational fusion. | |
| Pattern | Expression was observed in the intestine, hypodermis, seam cells, body-wall muscles and many neurons, oviduct sheath cell and spermatheca, coelomocytes, and pharyngeal and nerve ring. | ||
| Picture | WBPicture0000008781 | ||
| WBPicture0000008782 | |||
| WBPicture0000008783 | |||
| Remark | The intestinal phenotype of rab-10(dx2) and rab-10(q373) was completely rescued by the GFP-RAB-10 fusion protein, indicating that the expression pattern and subcellular localization of the reporters very likely reflect those of the endogenous protein. | ||
| Reference | WBPaper00027018 | ||
| Transgene | WBTransgene00001815 |
