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WormBase Tree Display for Expr_pattern: Expr4000

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Name Class

Expr4000Expression_ofGeneWBGene00003180
WBGene00003181
Reflects_endogenous_expression_ofWBGene00003180
WBGene00003181
Expression_dataLife_stageWBls:0000041
WBls:0000005
Anatomy_termWBbt:0004458Certain
WBbt:0004804Certain
WBbt:0005175Certain
WBbt:0006876Certain
GO_termGO:0005634
GO:0005737
Subcellular_localizationEmbryonic med transcripts accumulate in the EMS nucleus at the 4-cell stage, become cytoplasmic in MS and E.
TypeIn_situIn situ hybridization using an antisense med-1 probe, which detects both med-1 and med-2 transcripts owing to their 98% sequence identity.
PatternEmbryonic med transcripts accumulate in the EMS nucleus at the 4-cell stage, become cytoplasmic in MS and E, and are undetectable thereafter. Signal was also observed in the gonads of all adults, with 68% (174/257) showing very strong staining, while very little or no gonadal signal was observed using sense probes. Authors did not detect significant levels of med transcripts in very early embryos or late oocytes.
SpeciesCaenorhabditis briggsae
RemarkIn the related nematode, C. briggsae, in situ hybridization with a Cb-med-1 probe reveals gonadal as well as embryonic signal in EMS.
ReferenceWBPaper00028492