WormBase Tree Display for Expr_pattern: Expr4808
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| Expr4808 | Expression_of | Gene | WBGene00006794 |
|---|---|---|---|
| WBGene00002978 | |||
| WBGene00006819 | |||
| Reflects_endogenous_expression_of | WBGene00002978 | ||
| WBGene00006794 | |||
| WBGene00006819 | |||
| Expression_data | GO_term | GO:0005865 | |
| Subcellular_localization | Detailed immunolocalization studies revealed a preferential localization of UNC-87 to the center of the I-band region, whereas it was found to be absent from the distal edges of the thin filaments. Double staining of UNC-87 and actin showed a similar striated localization patterns for both proteins with no detectable signal at the dense bodies in the center of the striations. However, the band of UNC-87 was slightly narrower than that of actin, indicating that UNC-87 is absent from the distal portions of the thin filaments (near the pointed ends of the actin filaments). By contrast, CeTM has been shown previously to localize to the distal portion of the thin filaments, and, double staining of CeTM and UNC-87 indeed identified CeTM at the istal portion and UNC-87 at the central portion of the actin bands, albeit with some overlap. UNC-60B localized to the center of the actin bands between dense bodies, together with UNC-87. However, with the exception of this partial overlap, UNC-87 and UNC-60B mostly localized to different regions of the thin filaments. | ||
| Type | Antibody | ||
| Picture | WBPicture0000009077 | ||
| Remark | Picture: Figure 5. | ||
| Reference | WBPaper00030902 | ||
| Antibody_info | WBAntibody00000969 | ||
| WBAntibody00001283 |
