WormBase Tree Display for Expr_pattern: Expr744
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| Expr744 | Expression_of | Gene | WBGene00000884 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000884 | ||
| Expression_data | Life_stage | WBls:0000024 | |
| WBls:0000003 | |||
| WBls:0000038 | |||
| WBls:0000027 | |||
| WBls:0000035 | |||
| WBls:0000041 | |||
| Anatomy_term | WBbt:0003681 | ||
| WBbt:0005772 | |||
| Type | Reporter_gene | ||
| Pattern | cyp-8 protein as expression of beta-galactosidase was localized specifically in the gut cell nuclei. Expression is detected at all stages from embryo through to adult. Promoter region of Ce-CYP-8 examined with downstream coding sequence either including or excluding the NLS containing tail domain of cyp-8. This shows that non-cyclophilin tail domain directs the localization of this enzyme to the gut cell nuclei. Constructs containing promoter cyclophilin domain and tail domain exhibited nuclear localized gut staining in a non-nuclear localized vector. Animals transformed with the promoter and cyclophilin domain but lacking the NLS-rich tail domain show diffuse gut staining extending to the pharynx. | ||
| Remark | Reporter gene fusion type not specified. | ||
| This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope). | |||
| Reference | WBPaper00003528 | ||
| Transgene | WBTransgene00029788 |
