WormBase Tree Display for Expr_pattern: Expr8784

Expr8784 Expression_of: Gene: WBGene00006796
    Reflects_endogenous_expression_of: WBGene00006796
  Expression_data: Life_stage: WBls:0000024
      WBls:0000038
      WBls:0000027
      WBls:0000035
      WBls:0000041
      WBls:0000015
      WBls:0000021
    Anatomy_term (12)
  Type: Reporter_gene
  Pattern: unc-62::gfp expression was first detectable during mid-embryogenesis in a subset of cells that include AB lineage derivatives. In newly hatched L1 larvae, unc-62::gfp was observed in multiple cell types including the M mesoblast, as well as a few neurons in the head and tail, and dorsal and ventral hypodermis. In the L1 larva, unc-62::gfp expression continued throughout the M lineage in all dividing M descendants. The GFP signal was transiently detectable in M-derived CCs and BWMs before they terminally differentiate, but remained detectable in the SMs and throughout the SM lineage, including the differentiated vulval muscles. Outside of the M lineage, the neuronal expression in the head and tail was retained throughout postembryonic development, while hypodermal expression appeared more variable. unc-62::gfp expression was also observed in a subset of ventral nerve cord (VNC) cells after the L2 stage and in the P lineage with initial faint GFP expression in P3.p, P4.p and P5.p in L1 animals, which expanded to P6.p, P7.p and P8.p cells at the L2 stage. Upon vulval induction, L3 and L4 larvae displayed strong GFP expression in P5.p, P6.p and P7.p and their descendants, but expression in P3.p, P4.p and P8.p and their descendants became weaker and eventually undetectable by mid-L4 stage. unc-62::gfp expression persisted in all differentiated vulval cells after vulval morphogenesis in adults.
  Remark: Picture: Fig 4.
  Reference: WBPaper00035102
  Transgene: WBTransgene00030713