WormBase Tree Display for GO_term: GO:0043224
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| GO:0043224 | Name | nuclear SCF ubiquitin ligase complex | |
|---|---|---|---|
| Definition | A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). | ||
| Synonym | Exact | nuclear cullin complex | |
| nuclear SCF complex | |||
| nuclear Skp1/Cul1/F-box protein complex | |||
| Status | Valid | ||
| Type | Cellular_component | ||
| Parent | Instance_of | GO:0000152 | |
| GO:0019005 | |||
| Attributes_of | Index | Ancestor (17) | |
| Version | Gene Ontology releases/2023-11-15 |
