WormBase Tree Display for GO_term: GO:0071159
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| GO:0071159 | Name | NF-kappaB complex | ||
|---|---|---|---|---|
| Definition | A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. | |||
| Status | Valid | |||
| Type | Cellular_component | |||
| Child | Instance | GO:0035525 | ||
| Parent | Instance_of | GO:0140513 | ||
| Attributes_of | Index | Ancestor | GO:0005575 | |
| GO:0005622 | ||||
| GO:0005634 | ||||
| GO:0032991 | ||||
| GO:0043226 | ||||
| GO:0043227 | ||||
| GO:0043229 | ||||
| GO:0043231 | ||||
| GO:0110165 | ||||
| GO:0140513 | ||||
| Descendant | GO:0035525 | |||
| Version | Gene Ontology releases/2023-11-15 |
