WormBase Tree Display for Gene: HGNC:12502
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| HGNC:12502 | Identity | Name | CGC_name | Sumo1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name (22) | ||||||
| Public_name | Sumo1 | |||||
| DB_info | Database | HGNC | id | 12502 | ||
| AGR | cURI | HGNC:12502 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000116030 | ||||
| UniProt | UniProt_AC | P63165 | ||||
| OMIM | gene | 601912 | ||||
| DO | id | DOID:0080403 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00004888 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import | ||
| Experimental_info | Regulate_expr_cluster | WBPaper00038060:SUMO-1_downregulated | ||||
| WBPaper00038060:SUMO-1_upregulated |
