WormBase Tree Display for Gene: HGNC:14210
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| HGNC:14210 | Identity | Name | CGC_name | Sun2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name (12) | ||||||
| Public_name | Sun2 | |||||
| DB_info | Database | HGNC | id | 14210 | ||
| AGR | cURI | HGNC:14210 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000100242 | ||||
| UniProt | UniProt_AC | Q9UH99 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006816 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| Structured_description | Automated_description | SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010] | Inferred_automatically | AGR_import |
