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WormBase Tree Display for Gene: HGNC:3014

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Name Class

HGNC:3014IdentityNameCGC_nameDpysl2Inferred_automaticallyAGR_import
Other_name (15)
Public_nameDpysl2
DB_infoDatabaseHGNCid3014
AGRcURIHGNC:3014
EnsEMBLENSEMBL_geneIDENSG00000092964
UniProtUniProt_ACQ16555
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000963Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OrthoInspector
Panther
SonicParanoid
WBGene00006769Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
Panther
WBGene00000964Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]Inferred_automaticallyAGR_import