WormBase Tree Display for Gene: HGNC:3014
expand all nodes | collapse all nodes | view schema
HGNC:3014 | Identity | Name | CGC_name | Dpysl2 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (15) | ||||||
Public_name | Dpysl2 | |||||
DB_info | Database | HGNC | id | 3014 | ||
AGR | cURI | HGNC:3014 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000092964 | ||||
UniProt | UniProt_AC | Q16555 | ||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00000963 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
Inparanoid | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
WBGene00006769 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
Panther | ||||||
WBGene00000964 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
Inparanoid | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] | Inferred_automatically | AGR_import |