WormBase Tree Display for Gene: HGNC:3395
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| HGNC:3395 | Identity | Name | CGC_name | Ephb4 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name (15) | ||||||
| Public_name | Ephb4 | |||||
| DB_info | Database | HGNC | id | 3395 | ||
| AGR | cURI | HGNC:3395 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000196411 | ||||
| UniProt | UniProt_AC | P54760 | ||||
| OMIM | gene | 600011 | ||||
| DO | id | EFO:MONDO:0012016 | ||||
| DOID:264 | ||||||
| DOID:3748 | ||||||
| DOID:0081030 | ||||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006868 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
