WormBase Tree Display for Analysis: Microarray_Study.WBPaper00052845.ce.mr
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| Microarray_Study.WBPaper00052845.ce.mr | DB_info | Database | GEO | GSE81854 |
|---|---|---|---|---|
| Title | Grape seed extracts-mediated lipid mobility in C. elegans | |||
| Description | Oligomeric proanthocyanidins (OPCs) reduce triglycerides in the nematode C. elegans. Lipase was strongly inhibited in vitro accompanied by the reduction of total triglyceride storage capacity in vivo; Lipophilic staining was also attenuated in wild type worms and high-fat mutants exposed to OPCs. Apart from biochemical analyses, lipid metabolism was also genetically regulated, emphasizing the necessity to study underlying regulation mechanisms in intact animals. To gain a deeper insight into the potential gene targets of purified oligomeric proanthocyanidin trimer gallate (pOPC7), a binary microarray assay was carried out with wild type N2 populations continuously exposed to a bacterial diet with or without pOPC7. | |||
| Category | response to chemical | |||
| Microarray_experiment | WBPaper00052845:L4_control | |||
| WBPaper00052845:L4_pOPC7 | ||||
| Species_in_analysis | Caenorhabditis elegans | |||
| Reference | WBPaper00052845 |
