WormBase Tree Display for Gene: RGD:1586637
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| RGD:1586637 | Identity | Name | CGC_name | Ryr1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Ryr1 | |||||
| DB_info | Database | RGD | id | 1586637 | ||
| AGR | cURI | RGD:1586637 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000020557 | ||||
| UniProt | UniProt_AC | F1LMY4 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006801 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Enables ryanodine-sensitive calcium-release channel activity. Involved in several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; and response to purine-containing compound. Located in several cellular components, including sarcolemma; sarcomere; and sarcoplasmic reticulum. Is extrinsic component of cytoplasmic side of plasma membrane. Used to study myocardial infarction. Biomarker of osteochondrodysplasia and pulmonary hypertension. Human ortholog(s) of this gene implicated in congestive heart failure (multiple); intracranial vasospasm; and muscle tissue disease (multiple). Orthologous to human RYR1 (ryanodine receptor 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran. | Inferred_automatically | AGR_import |
