WormBase Tree Display for Gene: RGD:3639
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| RGD:3639 | Identity | Name | CGC_name | Scnn1a | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Scnn1a | |||||
| DB_info | Database | RGD | id | 3639 | ||
| AGR | cURI | RGD:3639 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000019368 | ||||
| UniProt | UniProt_AC | P37089 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006832 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00006748 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000950 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00003174 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000952 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00003168 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00012116 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| WBGene00022815 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Enables WW domain binding activity; actin binding activity; and ligand-gated sodium channel activity. Contributes to sodium ion transmembrane transporter activity. Involved in intracellular sodium ion homeostasis; regulation of body fluid levels; and sodium ion import across plasma membrane. Located in several cellular components, including acrosomal vesicle; apical plasma membrane; and sperm principal piece. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in Liddle syndrome; bronchiectasis 2; and pseudohypoaldosteronism. Orthologous to human SCNN1A (sodium channel epithelial 1 subunit alpha); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene. | Inferred_automatically | AGR_import |
