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WormBase Tree Display for Gene: RGD:61941

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Name Class

RGD:61941IdentityNameCGC_namerobo1Inferred_automaticallyAGR_import
Public_namerobo1
DB_infoDatabaseRGDid61941
AGRcURIRGD:61941
EnsEMBLENSEMBL_geneIDENSRNOG00000029614
UniProtUniProt_ACO55005
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00004729Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OrthoFinder
OrthoInspector
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables axon guidance receptor activity. Involved in several processes, including negative regulation of synapse assembly; nervous system development; and regulation of dendrite morphogenesis. Located in axon; dendrite; and neuronal cell body. Biomarker of diabetic retinopathy; lung non-small cell carcinoma; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in autosomal recessive congenital nystagmus; congenital nystagmus; multiple myeloma; panhypopituitarism; and plasmacytoma. Orthologous to human ROBO1 (roundabout guidance receptor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.Inferred_automaticallyAGR_import