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WormBase Tree Display for Gene: RGD:62004

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Name Class

RGD:62004IdentityNameCGC_nameCASKInferred_automaticallyAGR_import
Public_nameCASK
DB_infoDatabaseRGDid62004
AGRcURIRGD:62004
EnsEMBLENSEMBL_geneIDENSRNOG00000060946
ENSRNOG00000003054
UniProtUniProt_ACQ62915
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00002991Caenorhabditis elegansFrom_analysisInparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables PDZ domain binding activity; neurexin family protein binding activity; and protein kinase C binding activity. Involved in several processes, including positive regulation of dendritic spine morphogenesis; positive regulation of insulin secretion; and protein localization to plasma membrane. Located in several cellular components, including apical dendrite; basolateral plasma membrane; and podocyte foot. Part of protein-containing complex. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Orthologous to human CASK (calcium/calmodulin dependent serine protein kinase); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.Inferred_automaticallyAGR_import