WormBase Tree Display for Gene: RGD:62072

RGD:62072 Identity: Name: CGC_name: Slc18a3 Inferred_automatically: AGR_import
      Public_name: Slc18a3
    DB_info: Database: RGD id 62072
        AGR cURI RGD:62072
        EnsEMBL ENSEMBL_geneID ENSRNOG00000062141
        UniProt UniProt_AC Q62666
    Species: Rattus norvegicus
    Status: Live
  Gene_info: Biotype: SO:0001217
    Ortholog: WBGene00006756 Caenorhabditis elegans From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Enables acetylcholine:proton antiporter activity. Involved in acetylcholine uptake and neurotransmitter loading into synaptic vesicle. Located in axon terminus and synaptic vesicle. Part of AP-1 adaptor complex and AP-2 adaptor complex. Is active in cholinergic synapse; neuromuscular junction; and synaptic vesicle membrane. Biomarker of asthma and bladder disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 21. Orthologous to human SLC18A3 (solute carrier family 18 member A3); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine; 4-amino-2,6-dinitrotoluene. Inferred_automatically: AGR_import