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WormBase Tree Display for Gene: RGD:621520

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Name Class

RGD:621520IdentityNameCGC_nameKif1bInferred_automaticallyAGR_import
Public_nameKif1b
DB_infoDatabaseRGDid621520
AGRcURIRGD:621520
EnsEMBLENSEMBL_geneIDENSRNOG00000057626
UniProtUniProt_ACO88658
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006831Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionEnables several functions, including ATP hydrolysis activity; microtubule motor activity; and scaffold protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; dense core granule cytoskeletal transport; and response to rotenone. Located in cytoplasmic vesicle; mitochondrion; and neuron projection. Biomarker of amyotrophic lateral sclerosis and synucleinopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; hepatocellular carcinoma; multiple sclerosis; neuroblastoma; and ovary epithelial cancer. Orthologous to human KIF1B (kinesin family member 1B); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.Inferred_automaticallyAGR_import