WormBase Tree Display for Gene: RGD:69285
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| RGD:69285 | Identity | Name | CGC_name | Cfl1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Cfl1 | |||||
| DB_info | Database | RGD | id | 69285 | ||
| AGR | cURI | RGD:69285 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000020660 | ||||
| UniProt | UniProt_AC | P45592 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006794 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| WBGene00302980 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Enables actin filament binding activity; phosphatidylinositol bisphosphate binding activity; and protein phosphatase binding activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of cellular component organization; and positive regulation of cellular component organization. Acts upstream of or within cell projection organization and negative regulation of cell size. Located in several cellular components, including cofilin-actin rod; dendritic spine; and lamellipodium. Is active in glutamatergic synapse. Used to study myocardial infarction. Biomarker of several diseases, including epilepsy (multiple); impotence; muscular atrophy; ureteral obstruction; and vitamin B12 deficiency. Orthologous to human CFL1 (cofilin 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine. | Inferred_automatically | AGR_import |
