WormBase Tree Display for Disease_model_annotation: WBDOannot00000015
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WBDOannot00000015 | Disease_term | DOID:104 | |
---|---|---|---|
Disease_of_species | Homo sapiens | ||
Modeled_by | Disease_relevant_gene | WBGene00005153 | |
Association_type | is_implicated_in | ||
Evidence_code | GO_code | IMP | |
ECO_term | ECO:0007013 | ||
Genetic_sex | hermaphrodite | ||
Paper_evidence | WBPaper00006215 | ||
Disease_model_description | C. elegans is used as a model system to study bacterial adherence via biofilm formation and to identify genes in the infectious agent as well as the host that are required for infection; elegans srf-3, a nucleotide sugar transporter is implicated in adherence of bacteria via biofilms as mutants confer resistance to infection by Microbacterium nematophilum, and also prevent biofilm formation by Yersinia pseudotuberculosis, a close relative of the bubonic plague agent Yersinia pestis. | ||
Curator_confirmed | WBPerson324 | ||
Date_last_updated | 07 Nov 2023 00:00:00 |