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WormBase Tree Display for Disease_model_annotation: WBDOannot00000015

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Name Class

WBDOannot00000015Disease_termDOID:104
Disease_of_speciesHomo sapiens
Modeled_byDisease_relevant_geneWBGene00005153
Association_typeis_implicated_in
Evidence_codeGO_codeIMP
ECO_termECO:0007013
Genetic_sexhermaphrodite
Paper_evidenceWBPaper00006215
Disease_model_descriptionC. elegans is used as a model system to study bacterial adherence via biofilm formation and to identify genes in the infectious agent as well as the host that are required for infection; elegans srf-3, a nucleotide sugar transporter is implicated in adherence of bacteria via biofilms as mutants confer resistance to infection by Microbacterium nematophilum, and also prevent biofilm formation by Yersinia pseudotuberculosis, a close relative of the bubonic plague agent Yersinia pestis.
Curator_confirmedWBPerson324
Date_last_updated07 Nov 2023 00:00:00