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WormBase Tree Display for Disease_model_annotation: WBDOannot00001300

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Name Class

WBDOannot00001300Disease_termDOID:070355
Disease_of_speciesHomo sapiens
Modeled_byGenotypeWBGenotype00000137
Association_typeis_exacerbated_model_of
Evidence_codeGO_codeIMP
ECO_termECO:0007013
Modifier_infoModifier_geneWBGene00006816
Modifier_association_typecondition_exacerbated_by
Genetic_sexhermaphrodite
Paper_evidenceWBPaper00060317
Disease_model_descriptionKnocking down the LINC component, unc-84, enhances paralysis phenotypes in a nematode strain that expresses human A-beta (3-42) and impairs the ability of the worm to cope with proteotoxicity.
Curator_confirmedWBPerson324
Date_last_updated28 Jul 2022 00:00:00