WormBase Tree Display for Gene: WBGene00000047
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| WBGene00000047 | SMap | S_parent | Sequence | ZC504 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | acr-8 | Person_evidence | WBPerson1430 | |||||
| Sequence_name | ZC504.2 | ||||||||
| Molecular_name | ZC504.2 | ||||||||
| ZC504.2.1 | |||||||||
| CE53615 | |||||||||
| ZC504.2.2 | |||||||||
| Other_name | CELE_ZC504.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | acr-8 | ||||||||
| DB_info | Database | AceView | gene | XL33 | |||||
| WormQTL | gene | WBGene00000047 | |||||||
| WormFlux | gene | WBGene00000047 | |||||||
| NDB | locus_tag | CELE_ZC504.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000047|UniProtKB=Q23355 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 181246 | |||||||
| RefSeq | protein | NM_001375112.3 | |||||||
| TrEMBL | UniProtAcc | Q23355 | |||||||
| UniProt_GCRP | UniProtAcc | Q23355 | |||||||
| OMIM | gene | 100690 | |||||||
| 100710 | |||||||||
| 100720 | |||||||||
| 100725 | |||||||||
| 100730 | |||||||||
| 118503 | |||||||||
| 118505 | |||||||||
| 118507 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acr | ||||||||
| Allele (53) | |||||||||
| Strain | WBStrain00031896 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (77) | |||||||||
| Paralog (100) | |||||||||
| Structured_description | Concise_description | acr-8 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-8 falls into the 'ACR-8' class of nAChR subunits, which includes ACR-12 and ACR-13. | Paper_evidence | WBPaper00005223 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (30) | ||||||||
| Molecular_info | Corresponding_CDS | ZC504.2 | |||||||
| Corresponding_CDS_history | ZC504.2:wp54 | ||||||||
| ZC504.2:wp124 | |||||||||
| ZC504.2:wp272 | |||||||||
| Corresponding_transcript | ZC504.2.1 | ||||||||
| ZC504.2.2 | |||||||||
| Other_sequence (16) | |||||||||
| Associated_feature | WBsf718691 | ||||||||
| WBsf1006700 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058977 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr3704 | ||||||||
| Expr4340 | |||||||||
| Expr4979 | |||||||||
| Expr1012528 | |||||||||
| Expr1030022 | |||||||||
| Expr1162412 | |||||||||
| Expr2009197 | |||||||||
| Expr2027435 | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00006479 | ||||||||
| WBCnstr00006480 | |||||||||
| WBCnstr00011615 | |||||||||
| WBCnstr00037770 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction | WBInteraction000133959 | ||||||||
| WBInteraction000136793 | |||||||||
| WBInteraction000142026 | |||||||||
| WBInteraction000144320 | |||||||||
| WBInteraction000209431 | |||||||||
| WBInteraction000504009 | |||||||||
| WBInteraction000518504 | |||||||||
| WBInteraction000543443 | |||||||||
| Map_info | Map | X | Position | 2.18612 | Error | 0.001806 | |||
| Positive | Positive_clone | ZC504 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4886 | |||||||
| 4909 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
