WormBase Tree Display for Gene: WBGene00000095
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| WBGene00000095 | SMap | S_parent | Sequence | C25A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | aha-1 | Person_evidence | WBPerson698 | |||||
| Sequence_name | C25A1.11 | ||||||||
| Molecular_name | C25A1.11 | ||||||||
| C25A1.11.1 | |||||||||
| CE08377 | |||||||||
| Other_name | CELE_C25A1.11 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | aha-1 | ||||||||
| DB_info | Database | AceView | gene | 1K770 | |||||
| WormQTL | gene | WBGene00000095 | |||||||
| WormFlux | gene | WBGene00000095 | |||||||
| NDB | locus_tag | CELE_C25A1.11 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000095|UniProtKB=O02219 | |||||||
| family | PTHR23042 | ||||||||
| NCBI | gene | 172889 | |||||||
| RefSeq | protein | NM_001264398.3 | |||||||
| SwissProt | UniProtAcc | O02219 | |||||||
| UniProt_GCRP | UniProtAcc | O02219 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aha | ||||||||
| Allele (38) | |||||||||
| Strain | WBStrain00003018 | ||||||||
| WBStrain00036153 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (39) | |||||||||
| Ortholog (39) | |||||||||
| Structured_description | Concise_description | aha-1 encodes an ortholog of human aryl-hydrocarbon receptor nuclear translocator; AHA-1 interacts with AHR-1 and HIF-1 in vitro, requires HIF-1 for proper localization, and is expressed ubiquitously; AHA-1 also physically interacts with CKY-1, and when co-expressed in vitro, an AHA-1/CKY-1 complex exhibits sequence-specific DNA binding; when co-expressed in cultured cells, the AHA-1/CKY-1 complex can stimulate reporter gene transcription; | Paper_evidence | WBPaper00003028 | |||||
| WBPaper00004762 | |||||||||
| WBPaper00030846 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 05 Jan 2010 00:00:00 | ||||||||
| Automated_description | Enables DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; determination of adult lifespan; and social behavior. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in renal cell carcinoma and type 2 diabetes mellitus. Is an ortholog of human ARNT (aryl hydrocarbon receptor nuclear translocator) and ARNT2 (aryl hydrocarbon receptor nuclear translocator 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:700) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:700) | ||||||
| Molecular_info | Corresponding_CDS | C25A1.11 | |||||||
| Corresponding_CDS_history | C25A1.11b:wp273 | ||||||||
| Corresponding_transcript | C25A1.11.1 | ||||||||
| Other_sequence (88) | |||||||||
| Associated_feature | WBsf649561 | ||||||||
| WBsf655311 | |||||||||
| WBsf655312 | |||||||||
| WBsf664846 | |||||||||
| WBsf978557 | |||||||||
| WBsf220208 | |||||||||
| WBsf220209 | |||||||||
| Gene_product_binds (338) | |||||||||
| Transcription_factor | WBTranscriptionFactor000144 | ||||||||
| WBTranscriptionFactor000143 | |||||||||
| WBTranscriptionFactor000584 | |||||||||
| Experimental_info | RNAi_result (27) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00003518 | ||||||||
| WBCnstr00010171 | |||||||||
| WBCnstr00012978 | |||||||||
| WBCnstr00016013 | |||||||||
| WBCnstr00018172 | |||||||||
| WBCnstr00018230 | |||||||||
| WBCnstr00037738 | |||||||||
| Construct_product | WBCnstr00000624 | ||||||||
| WBCnstr00016688 | |||||||||
| WBCnstr00018230 | |||||||||
| WBCnstr00037738 | |||||||||
| Antibody | WBAntibody00000386 | ||||||||
| WBAntibody00002015 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (118) | |||||||||
| Interaction (85) | |||||||||
| Anatomy_function | WBbtf0281 | ||||||||
| Map_info | Map | I | Position | 4.74517 | Error | 0.004088 | |||
| Positive | Positive_clone | C25A1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4147 | |||||||
| 4252 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (34) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
