WormBase Tree Display for Gene: WBGene00000100
expand all nodes | collapse all nodes | view schema
WBGene00000100 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | ajm-1 | Person_evidence | WBPerson240 | |||||
Sequence_name | C25A11.4 | ||||||||
Molecular_name (42) | |||||||||
Other_name | jam-1 | ||||||||
H08J11.c | Curator_confirmed | WBPerson1983 | |||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
H08J11.a | |||||||||
H08J11.b | |||||||||
CELE_C25A11.4 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | ajm-1 | ||||||||
DB_info | Database | AceView | gene | XJ731 | |||||
WormQTL | gene | WBGene00000100 | |||||||
WormFlux | gene | WBGene00000100 | |||||||
NDB | locus_tag | CELE_C25A11.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9 | |||||||
family | PTHR21517 | ||||||||
NCBI | gene | 181148 | |||||||
RefSeq | protein (13) | ||||||||
SwissProt | UniProtAcc | A0A1C3NSL9 | |||||||
TrEMBL | UniProtAcc | H2KYC5 | |||||||
Q95ZY7 | |||||||||
UniProt_GCRP | UniProtAcc | A0A1C3NSL9 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00044785 | ||||
3 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00019173 | ||||
Acquires_merge | WBGene00044785 | ||||||||
WBGene00019173 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ajm | ||||||||
Allele (507) | |||||||||
Legacy_information | [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3 | ||||||||
Strain (22) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (24) | |||||||||
Ortholog (27) | |||||||||
Structured_description | Concise_description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | Paper_evidence | WBPaper00004765 | |||||
WBPaper00004961 | |||||||||
WBPaper00005194 | |||||||||
WBPaper00005946 | |||||||||
WBPaper00005969 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS (13) | ||||||||
Corresponding_CDS_history | C25A11.4b:wp254 | ||||||||
C25A11.4c:wp254 | |||||||||
C25A11.4d:wp254 | |||||||||
C25A11.4e:wp254 | |||||||||
Corresponding_transcript (16) | |||||||||
Other_sequence (84) | |||||||||
Associated_feature (76) | |||||||||
Experimental_info | RNAi_result (26) | ||||||||
Expr_pattern (20) | |||||||||
Drives_construct (23) | |||||||||
Construct_product (11) | |||||||||
Antibody | WBAntibody00000055 | ||||||||
WBAntibody00001322 | |||||||||
Microarray_results | SMD_C25A11.3 | ||||||||
SMD_C25A11.4 | |||||||||
SMD_H08J11_20.A | |||||||||
SMD_H08J11_21.A | |||||||||
SMD_H08J11_21.B | |||||||||
SMD_H08J11_21.C | |||||||||
175053_at | |||||||||
176976_at | |||||||||
176999_at | |||||||||
177037_at | |||||||||
188324_at | |||||||||
188333_s_at | |||||||||
189079_s_at | |||||||||
194256_x_at | |||||||||
A_12_P108793 | |||||||||
A_12_P109353 | |||||||||
A_12_P114727 | |||||||||
A_12_P118958 | |||||||||
A_12_P148290 | |||||||||
A_12_P148291 | |||||||||
A_12_P150035 | |||||||||
A_12_P150036 | |||||||||
A_12_P150037 | |||||||||
A_12_P150038 | |||||||||
A_12_P150039 | |||||||||
Aff_C25A11.3 | |||||||||
Aff_C25A11.4A | |||||||||
Aff_C25A11.4B | |||||||||
Aff_H08J11_20.A | |||||||||
Aff_H08J11_21.A | |||||||||
Aff_H08J11_21.B | |||||||||
Aff_H08J11_21.C | |||||||||
GPL13394_WBGene00000100 | |||||||||
GPL13394_WBGene00019173 | |||||||||
GPL13394_WBGene00044785 | |||||||||
GPL13914_C25A11.4 | |||||||||
GPL13914_F47E1.5 | |||||||||
GPL13914_H08J11.2 | |||||||||
GPL14144_C25A11.4a_3871-3930_0.923_11_B | |||||||||
GPL14144_C25A11.4a_4066-4125_0.910_13_C | |||||||||
GPL14144_C25A11.4a_4261-4320_0.953_1_A | |||||||||
GPL14144_F47E1.5_237-296_0.934_1_A | |||||||||
GPL14144_H08J11.2_319-378_0.918_7_C | |||||||||
GPL14144_H08J11.2_411-470_0.875_38_A | |||||||||
GPL14144_H08J11.2_601-660_0.947_2_B | |||||||||
GPL19516_CGZ0005834 | |||||||||
GPL19516_CGZ0005835 | |||||||||
GPL19516_CGZ0005836 | |||||||||
GPL19516_CGZ0005837 | |||||||||
GPL19516_CGZ0005838 | |||||||||
GPL19516_CGZ0022425 | |||||||||
GPL19516_CGZ0025970 | |||||||||
GPL21109_C25A11.4a | |||||||||
GPL21109_C25A11.4b | |||||||||
GPL21109_C25A11.4c | |||||||||
GPL21109_C25A11.4e | |||||||||
GPL21109_F47E1.5 | |||||||||
GPL21109_H08J11.2 | |||||||||
GPL3518_CE27083 | |||||||||
GPL3518_CE27084 | |||||||||
GPL3518_CE27182 | |||||||||
GPL8304_CE_WBGene00000100_A | |||||||||
GPL8304_CE_WBGene00000100_B | |||||||||
GPL8304_CE_WBGene00000100_C | |||||||||
GPL8304_CE_WBGene00019173_A | |||||||||
GPL8304_CE_WBGene00019173_B | |||||||||
GPL8304_CE_WBGene00044785_A | |||||||||
GPL8673_C25A11_4aP03438 | |||||||||
GPL8673_C25A11_4aP03728 | |||||||||
GPL8673_C25A11_4aP04333 | |||||||||
GPL8673_C25A11_4bP02644 | |||||||||
GPL8673_C25A11_4bP02648 | |||||||||
GPL8673_C25A11_4bP02656 | |||||||||
GPL8673_C25A11_4cP01951 | |||||||||
GPL8673_C25A11_4cP02373 | |||||||||
GPL8673_C25A11_4cP02847 | |||||||||
GPL8673_C25A11_4dP03315 | |||||||||
GPL8673_C25A11_4dP03605 | |||||||||
GPL8673_C25A11_4dP04210 | |||||||||
GPL8673_C25A11_4eP01042 | |||||||||
GPL8673_C25A11_4eP01464 | |||||||||
GPL8673_C25A11_4eP01938 | |||||||||
GPL8673_F47E1_5P00036 | |||||||||
GPL8673_F47E1_5P00081 | |||||||||
GPL8673_F47E1_5P00174 | |||||||||
GPL8673_H08J11_2P00228 | |||||||||
GPL8673_H08J11_2P00355 | |||||||||
GPL8673_H08J11_2P00695 | |||||||||
GPL9450_C25A11.4b | |||||||||
GPL9450_C25A11.4c | |||||||||
GPL9450_H08J11.2 | |||||||||
cea2.p.134751 | |||||||||
cea2.p.134795 | |||||||||
cea2.p.148436 | |||||||||
Expression_cluster (304) | |||||||||
Interaction (104) | |||||||||
Map_info | Map | X | Position | 0.672056 | Error | 0.047992 | |||
Positive | Positive_clone | C25A11 | Person_evidence | WBPerson506 | |||||
Author_evidence | Hardin JD | ||||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | Multi_point | 4150 | |||||||
Pseudo_map_position | |||||||||
Reference (133) | |||||||||
Remark | .3 gene was merged with .4 gene | ||||||||
Sequence connection from [Koppen M, Hardin JD] | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |