WormBase Tree Display for Gene: WBGene00000100
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| WBGene00000100 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ajm-1 | Person_evidence | WBPerson240 | |||||
| Sequence_name | C25A11.4 | ||||||||
| Molecular_name (42) | |||||||||
| Other_name | jam-1 | ||||||||
| H08J11.c | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| H08J11.a | |||||||||
| H08J11.b | |||||||||
| CELE_C25A11.4 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ajm-1 | ||||||||
| DB_info | Database | AceView | gene | XJ731 | |||||
| WormQTL | gene | WBGene00000100 | |||||||
| WormFlux | gene | WBGene00000100 | |||||||
| NDB | locus_tag | CELE_C25A11.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9 | |||||||
| family | PTHR21517 | ||||||||
| NCBI | gene | 181148 | |||||||
| RefSeq | protein (13) | ||||||||
| SwissProt | UniProtAcc | A0A1C3NSL9 | |||||||
| TrEMBL | UniProtAcc | H2KYC5 | |||||||
| Q95ZY7 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A1C3NSL9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00044785 | ||||
| 3 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00019173 | ||||
| Acquires_merge | WBGene00044785 | ||||||||
| WBGene00019173 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ajm | ||||||||
| Allele (507) | |||||||||
| Legacy_information | [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3 | ||||||||
| Strain (22) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (27) | |||||||||
| Structured_description | Concise_description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | Paper_evidence | WBPaper00004765 | |||||
| WBPaper00004961 | |||||||||
| WBPaper00005194 | |||||||||
| WBPaper00005946 | |||||||||
| WBPaper00005969 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS (13) | ||||||||
| Corresponding_CDS_history | C25A11.4b:wp254 | ||||||||
| C25A11.4c:wp254 | |||||||||
| C25A11.4d:wp254 | |||||||||
| C25A11.4e:wp254 | |||||||||
| Corresponding_transcript (16) | |||||||||
| Other_sequence | ACC07889_1 | ||||||||
| Tcol_isotig14940 | |||||||||
| Oden_isotig10512 | |||||||||
| ACC06794_1 | |||||||||
| PPC08871_1 | |||||||||
| NAC01499_1 | |||||||||
| NAC02003_1 | |||||||||
| BG734364.1 | |||||||||
| FC545266.1 | |||||||||
| MI06150 | |||||||||
| DN190386.1 | |||||||||
| JI164368.1 | |||||||||
| CR11467 | |||||||||
| NAC02138_1 | |||||||||
| TDC02311_1 | |||||||||
| Tcol_isotig23583 | |||||||||
| Acan_isotig18823 | |||||||||
| MH08522 | |||||||||
| Dviv_isotig12608 | |||||||||
| FC547969.1 | |||||||||
| PPC01532_1 | |||||||||
| EX537785.1 | |||||||||
| JI164151.1 | |||||||||
| EY469009.1 | |||||||||
| Tcol_isotig21073 | |||||||||
| FC540406.1 | |||||||||
| Dviv_isotig12607 | |||||||||
| Name_isotig01228 | |||||||||
| PP02110 | |||||||||
| Tcol_isotig17832 | |||||||||
| JO467863.1 | |||||||||
| EY461006.1 | |||||||||
| BU087991.1 | |||||||||
| ACC07234_1 | |||||||||
| CJC07433_1 | |||||||||
| FC545285.1 | |||||||||
| EY465684.1 | |||||||||
| BU088293.1 | |||||||||
| Oden_isotig20264 | |||||||||
| AAC00097_1 | |||||||||
| ACC22589_1 | |||||||||
| FC546968.1 | |||||||||
| Dviv_isotig25361 | |||||||||
| EY459091.1 | |||||||||
| Oden_isotig10510 | |||||||||
| DN153511.1 | |||||||||
| EY472384.1 | |||||||||
| Dviv_isotig23735 | |||||||||
| EY466282.1 | |||||||||
| GW410961.1 | |||||||||
| EX828503.1 | |||||||||
| Acan_isotig09049 | |||||||||
| CBC12633_1 | |||||||||
| MIC05787_1 | |||||||||
| HBC18049_1 | |||||||||
| JO468076.1 | |||||||||
| EY465771.1 | |||||||||
| GR15298 | |||||||||
| FC542950.1 | |||||||||
| CR03070 | |||||||||
| ACC20406_1 | |||||||||
| DN191253.1 | |||||||||
| Oden_isotig10511 | |||||||||
| Tcol_isotig13468 | |||||||||
| EX534739.1 | |||||||||
| Acan_isotig03385 | |||||||||
| BU088023.1 | |||||||||
| FC554486.1 | |||||||||
| CRC07708_1 | |||||||||
| CJC05100_1 | |||||||||
| FC540748.1 | |||||||||
| EX541620.1 | |||||||||
| PSC03297_1 | |||||||||
| FC554456.1 | |||||||||
| Acan_isotig12754 | |||||||||
| Dviv_isotig12609 | |||||||||
| EY470789.1 | |||||||||
| Acan_isotig03384 | |||||||||
| CR11468 | |||||||||
| FC541771.1 | |||||||||
| ACC27678_1 | |||||||||
| BU086898.1 | |||||||||
| EY467052.1 | |||||||||
| CRC03001_1 | |||||||||
| Associated_feature (76) | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern (20) | |||||||||
| Drives_construct (23) | |||||||||
| Construct_product (11) | |||||||||
| Antibody | WBAntibody00000055 | ||||||||
| WBAntibody00001322 | |||||||||
| Microarray_results (94) | |||||||||
| Expression_cluster (304) | |||||||||
| Interaction (104) | |||||||||
| Map_info | Map | X | Position | 0.672056 | Error | 0.047992 | |||
| Positive | Positive_clone | C25A11 | Person_evidence | WBPerson506 | |||||
| Author_evidence | Hardin JD | ||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4150 | |||||||
| Pseudo_map_position | |||||||||
| Reference (133) | |||||||||
| Remark | .3 gene was merged with .4 gene | ||||||||
| Sequence connection from [Koppen M, Hardin JD] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
