WormBase Tree Display for Gene: WBGene00000100

WBGene00000100 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 3
    Name: CGC_name: ajm-1 Person_evidence: WBPerson240
      Sequence_name: C25A11.4
      Molecular_name (42)
      Other_name: jam-1
        H08J11.c Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        H08J11.a
        H08J11.b
        CELE_C25A11.4 Accession_evidence: NDB BX284606
      Public_name: ajm-1
    DB_info: Database: AceView gene XJ731
        WormQTL gene WBGene00000100
        WormFlux gene WBGene00000100
        NDB locus_tag CELE_C25A11.4
        Panther gene CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9
          family PTHR21517
        NCBI gene 181148
        RefSeq protein (13)
        SwissProt UniProtAcc A0A1C3NSL9
        TrEMBL UniProtAcc H2KYC5
            Q95ZY7
        UniProt_GCRP UniProtAcc A0A1C3NSL9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 01 Jul 2016 14:56:15 WBPerson1983 Event: Acquires_merge: WBGene00044785
        3 01 Jul 2016 14:56:15 WBPerson1983 Event: Acquires_merge: WBGene00019173
      Acquires_merge: WBGene00044785
        WBGene00019173
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ajm
    Allele (507)
    Legacy_information: [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3
    Strain (22)
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (27)
    Structured_description: Concise_description: ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. Paper_evidence: WBPaper00004765
            WBPaper00004961
            WBPaper00005194
            WBPaper00005946
            WBPaper00005969
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS (13)
    Corresponding_CDS_history: C25A11.4b:wp254
      C25A11.4c:wp254
      C25A11.4d:wp254
      C25A11.4e:wp254
    Corresponding_transcript (16)
    Other_sequence (84)
    Associated_feature (76)
  Experimental_info: RNAi_result (26)
    Expr_pattern (20)
    Drives_construct (23)
    Construct_product (11)
    Antibody: WBAntibody00000055
      WBAntibody00001322
    Microarray_results (94)
    Expression_cluster (304)
    Interaction (104)
  Map_info: Map: X Position: 0.672056 Error: 0.047992
    Positive: Positive_clone: C25A11 Person_evidence: WBPerson506
          Author_evidence: Hardin JD
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4150
    Pseudo_map_position
  Reference: WBPaper00001900
    WBPaper00003842
    WBPaper00003843
    WBPaper00003844
    WBPaper00003933
    WBPaper00004124
    WBPaper00004382
    WBPaper00004493
    WBPaper00004780
    WBPaper00004961
    WBPaper00004964
    WBPaper00005123
    WBPaper00005256
    WBPaper00005355
    WBPaper00005372
    WBPaper00005576
    WBPaper00005605
    WBPaper00005653
    WBPaper00005946
    WBPaper00005969
    WBPaper00005972
    WBPaper00005975
    WBPaper00006072
    WBPaper00006196
    WBPaper00006315
    WBPaper00006400
    WBPaper00006422
    WBPaper00006462
    WBPaper00006463
    WBPaper00010071
    WBPaper00010189
    WBPaper00010419
    WBPaper00010477
    WBPaper00010548
    WBPaper00010843
    WBPaper00011311
    WBPaper00011601
    WBPaper00011872
    WBPaper00011874
    WBPaper00011905
    WBPaper00012320
    WBPaper00012324
    WBPaper00012331
    WBPaper00012424
    WBPaper00012425
    WBPaper00012427
    WBPaper00012494
    WBPaper00012560
    WBPaper00013425
    WBPaper00017601
    WBPaper00017616
    WBPaper00017617
    WBPaper00017629
    WBPaper00017732
    WBPaper00017733
    WBPaper00017734
    WBPaper00017744
    WBPaper00017747
    WBPaper00017748
    WBPaper00018098
    WBPaper00018122
    WBPaper00018126
    WBPaper00018355
    WBPaper00018360
    WBPaper00018407
    WBPaper00018447
    WBPaper00019574
    WBPaper00022970
    WBPaper00023223
    WBPaper00023279
    WBPaper00023331
    WBPaper00023371
    WBPaper00023797
    WBPaper00023815
    WBPaper00024189
    WBPaper00024194
    WBPaper00024262
    WBPaper00024453
    WBPaper00024738
    WBPaper00024817
    WBPaper00025137
    WBPaper00025711
    WBPaper00025995
    WBPaper00027236
    WBPaper00027244
    WBPaper00027245
    WBPaper00027285
    WBPaper00029033
    WBPaper00029128
    WBPaper00030654
    WBPaper00030899
    WBPaper00031082
    WBPaper00031697
    WBPaper00032325
    WBPaper00033357
    WBPaper00035979
    WBPaper00035982
    WBPaper00036205
    WBPaper00036947
    WBPaper00038491
    WBPaper00038669
    WBPaper00039779
    WBPaper00039809
    WBPaper00040632
    WBPaper00042781
    WBPaper00043621
    WBPaper00045462
    WBPaper00045913
    WBPaper00049111
    WBPaper00050122
    WBPaper00051878
    WBPaper00054726
    WBPaper00055090
    WBPaper00056902
    WBPaper00057033
    WBPaper00060134
    WBPaper00060787
    WBPaper00061621
    WBPaper00062248
    WBPaper00062488
    WBPaper00062715
    WBPaper00063071
    WBPaper00063252
    WBPaper00063926
    WBPaper00064069
    WBPaper00064208
    WBPaper00064685
    WBPaper00064788
    WBPaper00065085
    WBPaper00065626
    WBPaper00066105
    WBPaper00066161
    WBPaper00066295
  Remark: .3 gene was merged with .4 gene
    Sequence connection from [Koppen M, Hardin JD]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene