WormBase Tree Display for Gene: WBGene00000100
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WBGene00000100 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | ajm-1 | Person_evidence | WBPerson240 | |||||
Sequence_name | C25A11.4 | ||||||||
Molecular_name (42) | |||||||||
Other_name | jam-1 | ||||||||
H08J11.c | Curator_confirmed | WBPerson1983 | |||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
H08J11.a | |||||||||
H08J11.b | |||||||||
CELE_C25A11.4 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | ajm-1 | ||||||||
DB_info | Database | AceView | gene | XJ731 | |||||
WormQTL | gene | WBGene00000100 | |||||||
WormFlux | gene | WBGene00000100 | |||||||
NDB | locus_tag | CELE_C25A11.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9 | |||||||
family | PTHR21517 | ||||||||
NCBI | gene | 181148 | |||||||
RefSeq | protein (13) | ||||||||
SwissProt | UniProtAcc | A0A1C3NSL9 | |||||||
TrEMBL | UniProtAcc | H2KYC5 | |||||||
Q95ZY7 | |||||||||
UniProt_GCRP | UniProtAcc | A0A1C3NSL9 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00044785 | ||||
3 | 01 Jul 2016 14:56:15 | WBPerson1983 | Event | Acquires_merge | WBGene00019173 | ||||
Acquires_merge | WBGene00044785 | ||||||||
WBGene00019173 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ajm | ||||||||
Allele (507) | |||||||||
Legacy_information | [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3 | ||||||||
Strain (22) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (24) | |||||||||
Ortholog (27) | |||||||||
Structured_description | Concise_description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | Paper_evidence | WBPaper00004765 | |||||
WBPaper00004961 | |||||||||
WBPaper00005194 | |||||||||
WBPaper00005946 | |||||||||
WBPaper00005969 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS (13) | ||||||||
Corresponding_CDS_history (4) | |||||||||
Corresponding_transcript (16) | |||||||||
Other_sequence (84) | |||||||||
Associated_feature (76) | |||||||||
Experimental_info | RNAi_result (26) | ||||||||
Expr_pattern (20) | |||||||||
Drives_construct (23) | |||||||||
Construct_product (11) | |||||||||
Antibody | WBAntibody00000055 | ||||||||
WBAntibody00001322 | |||||||||
Microarray_results (94) | |||||||||
Expression_cluster (304) | |||||||||
Interaction (104) | |||||||||
Map_info | Map | X | Position | 0.672056 | Error | 0.047992 | |||
Positive | Positive_clone | C25A11 | Person_evidence | WBPerson506 | |||||
Author_evidence | Hardin JD | ||||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | Multi_point | 4150 | |||||||
Pseudo_map_position | |||||||||
Reference (133) | |||||||||
Remark | .3 gene was merged with .4 gene | ||||||||
Sequence connection from [Koppen M, Hardin JD] | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |