WormBase Tree Display for Gene: WBGene00000100
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| WBGene00000100 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
|---|---|---|---|---|---|---|---|
| Identity (6) | |||||||
| Gene_info | Biotype | SO:0001217 | |||||
| Gene_class | ajm | ||||||
| Allele (507) | |||||||
| Legacy_information | [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3 | ||||||
| Strain (22) | |||||||
| RNASeq_FPKM (74) | |||||||
| GO_annotation (24) | |||||||
| Ortholog (27) | |||||||
| Structured_description | Concise_description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | Paper_evidence | WBPaper00004765 | |||
| WBPaper00004961 | |||||||
| WBPaper00005194 | |||||||
| WBPaper00005946 | |||||||
| WBPaper00005969 | |||||||
| Curator_confirmed | WBPerson48 | ||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
| Automated_description | Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). | Paper_evidence | WBPaper00065943 | ||||
| Curator_confirmed | WBPerson324 | ||||||
| WBPerson37462 | |||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
| Molecular_info | Corresponding_CDS (13) | ||||||
| Corresponding_CDS_history | C25A11.4b:wp254 | ||||||
| C25A11.4c:wp254 | |||||||
| C25A11.4d:wp254 | |||||||
| C25A11.4e:wp254 | |||||||
| Corresponding_transcript (16) | |||||||
| Other_sequence (84) | |||||||
| Associated_feature (76) | |||||||
| Experimental_info | RNAi_result (26) | ||||||
| Expr_pattern (20) | |||||||
| Drives_construct (23) | |||||||
| Construct_product (11) | |||||||
| Antibody | WBAntibody00000055 | ||||||
| WBAntibody00001322 | |||||||
| Microarray_results (94) | |||||||
| Expression_cluster (304) | |||||||
| Interaction (104) | |||||||
| Map_info | Map | X | Position | 0.672056 | Error | 0.047992 | |
| Positive | Positive_clone | C25A11 | Person_evidence | WBPerson506 | |||
| Author_evidence | Hardin JD | ||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | Multi_point | 4150 | |||||
| Pseudo_map_position | |||||||
| Reference (133) | |||||||
| Remark | .3 gene was merged with .4 gene | ||||||
| Sequence connection from [Koppen M, Hardin JD] | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
| Method | Gene |
