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WormBase Tree Display for Gene: WBGene00000164

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Name Class

WBGene00000164SMapS_parentSequenceF53H8
IdentityVersion2
NameCGC_nameapm-3Person_evidenceWBPerson360
WBPerson567
Sequence_nameF53H8.1
Molecular_nameF53H8.1
F53H8.1.1
CE35723
Other_nameapt-7Person_evidenceWBPerson625
CELE_F53H8.1Accession_evidenceNDBBX284606
Public_nameapm-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
201 Apr 2005 11:05:24WBPerson2970Name_changeCGC_nameapm-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classapm
Allele (34)
StrainWBStrain00003476
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOPX012
Ortholog (38)
ParalogWBGene00000150Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001082Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006777Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006829Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionapm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.Paper_evidenceWBPaper00004103
WBPaper00004907
WBPaper00005520
WBPaper00013041
WBPaper00025094
Curator_confirmedWBPerson1843
WBPerson324
WBPerson567
Date_last_updated23 Jan 2007 00:00:00
Automated_descriptionInvolved in lipid storage and lysosome organization. Predicted to be located in cytoplasmic vesicle. Predicted to be part of clathrin adaptor complex. Expressed in muscle cell; pharynx; spermatheca; and vulva. Is an ortholog of human AP3M1 (adaptor related protein complex 3 subunit mu 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF53H8.1
Corresponding_CDS_historyF53H8.1:wp108
Corresponding_transcriptF53H8.1.1
Other_sequence (63)
Associated_featureWBsf647808
WBsf662451
WBsf1003904
WBsf1022191
WBsf235299
Experimental_infoRNAi_result (11)
Expr_patternExpr3688
Expr6161
Expr12910
Expr1024542
Expr1030093
Expr1152010
Expr2009362
Expr2027598
Drives_constructWBCnstr00003937
WBCnstr00011600
WBCnstr00037694
Construct_productWBCnstr00022947
WBCnstr00023054
WBCnstr00037694
Microarray_results (22)
Expression_cluster (144)
Interaction (27)
Map_infoMapXPosition-18.8908Error0.004786
PositivePositive_cloneF53H8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4163
4512
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene